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1208 technologies found
page 6 of 61
The Invention The Glaucoma Implant is a new shunt that eliminates the complications created by devices currently in use and it may eliminate the need for repeat surgeries. It is small in size, easy to implant and thus causes less discomfort for the patient and results in faster recovery time. ...
Scientific Contact: Arieh S. Solomon
Description of Technology The present invention relates to methods and materials for the photochemical functionalization of parylene (poly(p-xylylene)) films using a wide range of functional organic molecules/reagents as well as polymeric polycarboxylated (polyCOOH) (nano)particles based on ...
Scientific Contact: Jean-Paul Lellouche
Inflammation often named “the secret killer” is a key factor in a large group of diseases affecting and killing millions of people every year. Examples of inflammatory diseases or diseases with key inflammatory components include Arthritis, Alzheimer, Parkinson, ALS, Peritonitis, Colitis, ...
Scientific Contact: Rachel Levy
The TechnologyCharacterization of pathologies related to macromolecules (MM) can now be carried out in a more comprehensive manner using these new MRI sequences. For example: Collagen in connective tissue and myelin in the nerves of brain and spinal cord are imaged with intensity proportional ...
Scientific Contact: Gil Navon
Lab Description The general purpose of my research is to describe the genetic and endocrine regulation of bone metabolism. To this end, we developed expertise in most aspects of bone research, from in vivo models, imaging of bone microarchitecture, in vitro cell cultures and molecular biology. ...
Scientific Contact: Yankel Gabet
Animal eye models for evaluation of systemic and topical use of new medications, devices and delivery systems. The models include external eye, intraocular, orbital, and optic nerve ...
Scientific Contact: Arieh S. Solomon
Female mice are fed with diets rich in specific f.a. (saturated or unsaturated) during pregnancy and/or lactation. The offspring is raised on a regular diet or on a fat rich diet, and develops obesity, fatty liver, and insulin resistance, depending on the diet received in utero. The model ...
Scientific Contact: Alicia Leikin-Frenkel
In vitro and in vivo animal models for stroke, Alzheimer's disease (AD), and multiple sclerosis (MS). Rapid screening method for selecting candidates with specific insulin-degrading enzyme inhibitor activity in Types I and II Diabetes. ...
Scientific Contact: Dan Frenkel
The Tel-Aviv University (TAU) holds several regular and SPF (Specific Pathogen Free) animal care facilities, providing state-of-the-art non-clinical and pre-clinical laboratory research services.We can perform multi-level studies, using a large variety of animals and supply veterinarian ...
Scientific Contact: Mickey Harlev
Need: There is a strong need for novel targeted based approaches for type II diabetes management. Innovation: We propose to develop selective antagonist for novel target to reduce beta-cell damage as a potential treatment for type 2 diabetes. We provide the first evidence of rescuing ...
Scientific Contact: Danielle Melloul
Summary Novel treatment for angiogenesis-related diseases. Angiogenesis — the growth of new blood vessels from pre-existing vasculature — has an essential role in development, reproduction and repair. Pathological angiogenesis is a common theme in a broad range of diseases such as cancer, ...
Scientific Contact: Karina Yaniv
Need: There is a need for novel compounds with anti-biofilm activity to increase susceptibility of certain bacterial strains towards conventional antibiotics. Innovation: We have developed novel compounds with anti-biofilm activity. We are proposing to use our compounds as a potential ...
Scientific Contact: David Enk
Summary Novel peptide sequences identified from breast, prostate, and bladder cancers are utilized as targets for anti-tumor vaccines. Local therapy such as surgical excision or ablation by radiation is a mainstay for the treatment of primary cancer and is curative for a percentage of the ...
Scientific Contact: Lea Eisenbach
Summary A monoclonal antibody against GluR3B, a peptide found in epilepsy patients, and especially in patients suffering from intractable, resistant forms of the disease, could be used in diagnosis kits as well as in drug development for this form of "autoimmune epilepsy". Applications ...
Scientific Contact: Mia Levite
Need: Antimicrobial surfaces have been a major challenge particularly in medicine where microbial agents tend to accumulate and propagate onto implantable devices made of various materials, particularly onto polymers. For example, indwelling catheters have to be removed sometimes shortly after ...
Scientific Contact: Ervin Weiss
Antibodies from mouse lymphoma cells recognize human breast cancer Categories Oncology, breast cancer diagnosis and treatment, antibodies Development Stage Positive results obtained in mice and in small number of human samples Patent Status U.S. patent pending, PCT publication ...
Scientific Contact: Jacob Hochman
monoclonal antibodies against cancer cells and cancer stem cells MUC1 has long been of interest for targeted tumor therapy. Cleavage of MUC1 yields an extracellular alpha subunit non-covalently bound to a smaller cell-surface beta subunit. Because the MUC1 alpha subunit is released into the ...
Scientific Contact: Daniel H. WRESCHNER
Summary Improved immunotherapy for breast cancer. Monoclonal antibodies (mAbs) to ErbB-2/HER2 growth factor receptor, or to its sibling, the epidermal growth factor receptor (EGFR), prolong survival of cancer patients, especially when combined with cytotoxic therapies. However, low ...
Scientific Contact: Yosef Yarden
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