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532 technologies found
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Our Innovation Based on a provocative working hypothesis, we most probably identified the molecular origin of insulin resistance (IR). Systemic IR is induced via post-translational modification (PTM) of liver key regulatory proteins. We have discovered that hepatic futile utilization of ...
Scientific Contact: Shmuel Ben-Sasson
Background One of the main obstacles for successful cryopreservation of cells is the irreversible damage to cells organelles and membranes caused by uncontrolled growth of ice in super-cooled liquid. This has a crucial impact on organ, embryo, tissue, and blood storage and transportation in ...
Scientific Contact: Ido Braslavsky
12E12 (Yeda)
Summary Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry. Leukotrienes: Veterinary drugs: § 130 - Anti-idiotypic antibody against ...
Scientific Contact: Fortune Kohen
15-mer (Yeda)
Summary 236-237 - Diastereomer Lytic Peptides for Treatment of Solid Tumors and Metastasis Description: 15-mer (Leu-Lys-Dleu- Leu-Lys-Dlys-Leu-Dleu-Dlys-Lys-Leu-Leu-Dlys-Leu-Leu) and 15-mer Histidin (H-Leu-Lys-D-Leu- Leu-His-D-Lys-Leu-D-Leu-D-Lys-His-Leu-Leu-D-Lys-Leu-Leu-NH2) are ...
Scientific Contact: Yechiel Shai
Summary 236-237 - Diastereomer Lytic Peptides for Treatment of Solid Tumors and Metastasis Description: 15-mer (Leu-Lys-Dleu- Leu-Lys-Dlys-Leu-Dleu-Dlys-Lys-Leu-Leu-Dlys-Leu-Leu) and 15-mer Histidin (H-Leu-Lys-D-Leu- Leu-His-D-Lys-Leu-D-Leu-D-Lys-His-Leu-Leu-D-Lys-Leu-Leu-NH2) are ...
Scientific Contact: Yechiel Shai
Human embryonic stem (hES) cells hold promise as an unlimited source of cells for transplantation therapies. The present invention is a method for the control of hES cell proliferation and differentiation into complex, viable 3D tissue constructs. The invention describes the use of biodegradable ...
The present invention provides an advanced tissue-engineering technique for the development of 3D co-culture systems that reconstruct vascularization of pancreatic tissue ex-vivo. In this novel engineered 3D pancreatic model, isolated pancreatic islets can be co-cultured with endothelial cells. The ...
499F (Yeda)
Summary Monoclonal antibodies specific to cholesterol/ceramide mixture Description: Monoclonal antibodies specific for cholesterol/ceramide-rich domains (clones 405F, 14F, 499F) and cholesterol micro-domains (clones 36A1, 5881) in cell membranes. Originally raised against an artificial ...
Scientific Contact: Lia Addadi
Summary Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry. Isoflavones: § 155 – Monoclonal antibody to 7-(O)-carboxymethyl ...
Scientific Contact: Fortune Kohen
Summary A DNP-specific murine IgE monoclonal antibody Description: Hybridoma line producing large amounts of reaginic (IgE) anti-DNP monoclonal antibody (clone SPE-7), which was generated by the fusion of splenic lymphocytes from C57BL/6 mice and the NSI plasmacytoma cell line. The monoclonal ...
Scientific Contact: Zelig Eshhar
The ProblemPresently the most widely employed micro projectile gun methods involves the use of gas-driven acceleration to launch high velocity DNA coated gold or titanium micro particles which puncture and penetrate cells. The SolutionOur innovative, very promising gene gun technology can be made ...
Scientific Contact: Orit Shefi
Scientific Contact: Claude Brodski
Background There is a growing demand in the field of biological drugs for improved protein expression platforms. Consequently there is a need for affordable manufacturing methods. Our Innovation A new concept of vector design that incorporates a gene-specific enhanced translation elements and ...
Scientific Contact: Boaz Tirosh
Summary Rapid, label free assay for glycan identification, accessible for use in medical diagnostics and biomanufacturing quality control. While glycans hold great promise as biomarkers for several diseases including cancer, technologies that enable rapid and sensitive glycan analysis for ...
Scientific Contact: David Margulies
Prostate cancer (CaP), an adenocarcinoma of the prostate, is the most common cancer in American males over the age of 55 and the second cause of cancer-related mortality. The current diagnosis of prostate cancer is based on the measurements of serum prostate-specific antigen (PSA) levels. ...
Though the brain has relatively high blood flow, it remains one of the least accessible organs for drug delivery due to the blood-brain barrier (BBB) and cerebrospinal fluid barrier, which separate the brain from its blood supply and control the movement of compounds in and out of the brain. Our ...
Background The release of targeted drugs is often achieved by attaching the drug load to a carrier through specific peptide sequences which are cleaved by proteases that are highly expressed at the desired location. Cathepsins proteases, whose activity and expression are highly elevated in ...
Scientific Contact: Galia Blum
Category Life Sciences &Diagnostic Keywords IBD, clock circadian ,Colitis, Diagnostic tool, Crohn, Systemic diseases, Inflammation disease Current Development stage General list: TRL5 Technology validated in relevant environment ...
Scientific Contact: Oren Froy
Category LifeSciences and BioTechnology Keywords Pain, Opioid receptor, Addiction, Opioid addiction, Narcotics, Analgesia Application Severe, high-impact chronic pain affects 20 million people in the US annually, and presents a common, difficult-to-treat clinical challenge. ...
Scientific Contact: Shmuel Ben-Sasson
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*TTO - Technology Transfer Organization
ITTN - Israel Tech Transfer Organization