Technology Opportunities

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3D Printing of 100% Wood and Wood Plastic Composites (Yissum)
Background Current manufacturing and processing of wood uses hazardous materials and traditional low-tech methods. The existing methods require significant manpower, but more importantly, limits the versatility and personalization of the products. Hazardous materials that are currently ...
Scientific Contact: Shlomo Magdassi
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A Diagnostic tool for specific bacterial detection (Pseudomonas aeruginosa) (Yeda)
Summary Highlights Pseudomonas aeruginosa bacteria are common pathogens that are difficult to treat and are therefore critical to diagnose early when involved in infections. The commonly used method for confirming a P. aeruginosa infection is cultural inoculation, which takes 2-3 days to ...
Scientific Contact: Noam Sobel
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A Method in Improving Survival and Expansion of Hematopoietic Stem Cells (Yeda)
Summary hematopoietic cells. HSCs have the capacity to both self-renew and to differentiate, and they migrate from the bone marrow to the blood upon demand. Since HSCs can differentiate to a variety of cell types, including immune system cells, they have a huge therapeutic potential. Indeed, ...
Scientific Contact: Idit Shachar
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A novel and facile method for 3D printing using Ceramic Inks (Yissum)
Background Current 3D printing processes for ceramic 3D structures is conducted mainly by printing an object, which is composed of a ceramic powder and an organic binder, then sintering the body at a high temperature (>1000 °C). The current ceramic 3D-printing processes are mainly ...
Scientific Contact: Shlomo Magdassi
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A Novel Approach for Controlling Gene Expression (Arbirtium - a Novel approach) (Yeda)
Summary One of the challenges in the areas of synthetic biology and its clinical applications, is the capacity to control the induction of different genes, whether for the purpose of activating genetic circuits or inducing the expression of a specific protein. Present approaches are limited to ...
Scientific Contact: Rotem Sorek
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A Novel Approach for Treating Cancer and Collagen-Associated Diseases by Using Anti-LOXL-2 Antibody (Yeda)
Summary Disruption to the Extra-Cellular Matrix (ECM) is associated with many pathological conditions, such as various cancer types and tissue fibrosis, and also correlates with high tumor malignancy. Therefore, controlling ECM composition and morphology is considered a potential treatment for ...
Scientific Contact: Irit Sagi
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A Novel Method for Detecting Activation of Necroptosis via Exosome Analysis (Yeda)
Summary Numerous medical conditions are related to inflammation, such as pancreatitis, psoriasis, inflammatory bowel disease, atherosclerosis, neurodegeneration, and more. However, determination of inflammation in the body, especially at early stages of a pathology is difficult to assess. ...
Scientific Contact: David Wallach
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A Novel Method for Treating Drug-Resistant Lung Cancer Using a Combination of Antibodies (Yeda)
Summary A novel method for treating tyrosine kinase inhibitor (TKI)-resistant cancer, by using a combination of three different antibodies. Lung cancer is known as one of the most fatal forms of cancer. Notably, standard treatments for other cancer types (e.g. TKIs and mAbs), have shown only a ...
Scientific Contact: Yosef Yarden
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A Novel Method of Preventing or Treating Secondary Infections by Inhibition of Membrane Type I Matrix-Metalloproteinase-1 (Yeda)
Summary A novel method of preventing secondary infections, by inhibition of membrane type I matrix-metalloproteinase-1 (MT1-MMP), which reduces degradation of the extra-cellular matrix. Pathogens that infect the respiratory system are the cause of some of the most dangerous infections, ...
Scientific Contact: Irit Sagi
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A Novel Method of Treating Cancer by Targeting EGFR Ligand Amphiregulin (Yeda)
Summary A novel method for treating ovarian cancer by intercepting the EGFR ligand amphiregulin, when elevated expression levels are found in a patient. Ovarian cancer represents a relatively common type of cancer that affects women. However, the primary therapeutic option for ovarian cancer ...
Scientific Contact: Yosef Yarden
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A Novel Process for Fabricating Boron Carbide-Copper Cermets (BGN)
This novel invention presents a cost effective process for the fabrication of ceramics packed with metal. These cermets composites are based on Boron Carbides with infiltrated copper. The process addresses the design of B4C and Cu cermets with two interpenetrating and interconnected networks of B4C ...
Scientific Contact: Moshe Dariel
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A Novel Target for Inducing Myelinating Activity of Oligodendrocytes (Yeda)
Summary The proper functioning of the central nervous system (CNS) depends on effective communication between different neurons. A fundamental process ensuring said communication is myelination, which acts to insulate projections of neurons (axons) to ensure efficient transmittance of ...
Scientific Contact: Elior Peles
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A Novel Technique to Produce Large Quantities of Therapeutic T cells (Yeda)
Summary Culturing and expanding T cells ex-vivo, while retaining their functionality, is an essential factor for the development of cutting-edge immunotherapies. A major problem frequently faced by physicians is the low number of T cells available for adoptive immunotherapy, and the difficulty ...
Scientific Contact: Benjamin Geiger
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A Novel Tunable Micro-Disk (BGN)
This invention discusses a micro-scale optical device that includes a tunable micro disk resonator possessing a high quality factor. The device comprises of a waveguide and a micro-disk, optically coupled to the waveguide. The high quality factor allows for a single photon to interact several times ...
Scientific Contact: Ron Folman
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A TACE inhibitor (ADAM17) (Yeda)
Summary New generation of superior nature-inspired therapeutics for treating inflammation.Inflammation is characterized by elevated levels of TNF-?. Neutralizing TNF-? activity was shown to be beneficial for patients with chronic autoimmune inflammatory diseases such as rheumatoid arthritis ...
Scientific Contact: Irit Sagi
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Acquisition of Multidimensional NMR Spectra in a Single Scan (Yeda)
Summary A method to significantly shorten acquisition times of high-quality MRI images. Multidimensional nuclear magnetic resonance (NMR) is used nowadays in many applications (e.g., discovery of new pharmaceutical drugs, characterization of new catalysts, and investigation of the structure and ...
Scientific Contact: Lucio Frydman
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Advanced Membranes for Water Desalination, (BGN)
Membranes are an important technological component in the development of sustainable technologies. Membrane processes are inherently less energy consuming, more highly efficient in the required separation process and are significantly less polluting unit operations then competitive processes such ...
Scientific Contact: Yoram Oren
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Affinity Maturated T-Cell Receptor (Yeda)
Summary Immunotherapy, that is the use of the immune system to treat cancer, is currently a leading candidate in the combat against cancer. Unlike the toxic effects of both chemotherapy and radiation, immunotherapy is considered to have mild side effects due to its ability to differentiate ...
Scientific Contact: Rachel Lea Eisenbach
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ANTI-INFECTIOUS COATING FOR IMPLANTS (Yissum)
Reches Meital, HUJI, Faculty of Science, The Institute of Chemistry Background The surface chemistry and topography of implants are very important to their design. This is because the interface between the implant and the human body will determine how well the implant would integrate in the ...
Scientific Contact: Meital Reches
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Antibodies directed to ErbB ligandsfor treating cancer (Yeda)
Summary A tailor-made strategy for cancer treatment. The ErbB family of tyrosine kinase receptors and their ligands play important roles in development and tissue remodeling throughout adulthood. ErbB proteins are involved in several types of human cancer. Clinical studies indicate that ...
Scientific Contact: Yosef Yarden
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