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BACKGROUNDLeishmania parasites cycle between two hosts, insect host and mammalian macrophages. Infection in the mammalian host is caused by proliferation within macrophages, especially present in liver and spleen (visceral) or within macrophages in the skin (cutaneous Leishmaniasis). Leishmania ...
Scientific Contact: Shulamit Michaeli
The Problems1. Drug addiction is a scourge of both developed and less-developed societies. The economic impact of drug addiction includes direct treatment costs as well as lost productivity and crime. 2. Neuropathic pain is a chronic pain condition caused by a primary lesion or dysfunction in the ...
Scientific Contact: Gal Yadid
The ProblemAge-Related Macular Degeneration (AMD) and Diabetic Retinopathy (DR) are leading causes of blindness in the Western world. Both are characterized by pathological angiogenesis in the various eye structures. Current treatment for AMD and DR includes monthly intraocular injection of various ...
Scientific Contact: Yossi Mandel
The ProblemImmunotherapy has become a revolution in the area of cancer treatment. Compared to the traditional methods, such as invasive surgeries, radiation and chemotherapy, immunotherapy is more specific and less toxic to patients. Chimeric antigen receptor (CAR)-engineered T cell therapy is ...
Scientific Contact: Cyrille Cohen
The ProblemDe-regulation of Robo receptors appear in a number of diseases and types of cancer and the therapeutic potential for drugs that will modulate Robo activities is therefore high, but no such drugs exist. The SolutionNovel structure-based design of agonistic and antagonistic antibodies for ...
Scientific Contact: Yarden Opatowsky
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*TTO - Technology Transfer Organization
ITTN - Israel Tech Transfer Organization