Technology Opportunities

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3D tissue structures using differentiating embryonic stem cells (Technion)
Human embryonic stem (hES) cells hold promise as an unlimited source of cells for transplantation therapies. The present invention is a method for the control of hES cell proliferation and differentiation into complex, viable 3D tissue constructs. The invention describes the use of biodegradable ...
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3D vascularized pancreatic islets - for islets transplantation (Technion)
The present invention provides an advanced tissue-engineering technique for the development of 3D co-culture systems that reconstruct vascularization of pancreatic tissue ex-vivo. In this novel engineered 3D pancreatic model, isolated pancreatic islets can be co-cultured with endothelial cells. The ...
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A method for Evaluating A Mental Disorder (BGN)
Scientific Contact: Claude Brodski
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A Method of Treating Neurodegenerative Diseases (BGN)
Scientific Contact: Alon Monsonego
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A New Biomarker for early Prostate Cancer detection (BioRap)
Prostate cancer (CaP), an adenocarcinoma of the prostate, is the most common cancer in American males over the age of 55 and the second cause of cancer-related mortality. The current diagnosis of prostate cancer is based on the measurements of serum prostate-specific antigen (PSA) levels. ...
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A new drug and gene delivery system to the brain (Technion)
Though the brain has relatively high blood flow, it remains one of the least accessible organs for drug delivery due to the blood-brain barrier (BBB) and cerebrospinal fluid barrier, which separate the brain from its blood supply and control the movement of compounds in and out of the brain. Our ...
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A Novel Alginate Hydrogel Based Controlled and Targeted Delivery System (BGN)
Controlled drug delivery systems offer numerous advantages compared to conventional dosage forms including improved efficacy, reduced toxicity, and improved patient compliance and convenience. Controlled release systems aim to improve the effectiveness of drug therapy. This improvement can take ...
Scientific Contact: Smadar Cohen
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A Novel Hydrogel Based Injectable Bilayer Device for Simultaneous Regeneration of Articular Cartilage and Subchondral Bone (BGN)
A subchondral defect is usually characterized by a structural breakdown of the articular cartilage and the bone underneath due to trauma or disease, leading to chronic disabilities. Treating such defects is an important medical target since in the adult patient, damaged cartilage cannot ...
Scientific Contact: Smadar Cohen
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A novel medical device for the treatment of Hallux Valgus (Mor)
Scientific Contact: Dror Robinson
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A Novel Non-Hormonal Composition as Contraceptive for Ovulation (Tel Hashomer)
A Novel Non-Hormonal Composition as Contraceptive for Ovulation Ariel Hourvitz, Yuval Yung, Svetlana Markman and Gil Yerushalmi, Sheba Medical Center Categories Women Health , Contraceptive Composition, Fertility, Non Hormonal Development Stage Preclinical studies – efficacy and ...
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A Novel Non-Hormonal Composition as Contraceptive for Ovulation (Tel Hashomer)
A Novel Non-Hormonal Composition as Contraceptive for Ovulation Ariel Hourvitz, Yuval Yung, Svetlana Markman and Gil Yerushalmi, Sheba Medical Center Categories Women Health , Contraceptive Composition, Fertility, Non Hormonal Development Stage Preclinical studies – efficacy and ...
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A novel strategy for treating melanoma development and resistance (Technion)
The present technology describes the caspase-3/YAP module as a new target for the treatment of melanoma development and ...
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A Novel Treatment for Leaking Blebs (Mor)
Background Glaucoma is a disease characterized by intra-ocular pressure sufficient to damage the optic nerve and cause permanent impairment of vision. Glaucoma is rarely cured, but its progression can be greatly delayed by reducing the intra-ocular pressure with medicines, laser procedure or ...
Scientific Contact: Orna Geyer
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A Novel Treatment of Streptococcus pneumoniae Infections (BGN)
Streptococcus pneumoniae (S. pneumonia) is part of the flora of the human respiratory tract, and can cause mucosal and invasive infections such as otitis media, pneumonia, sepsis and meningitis. The mucosal epithelial surfaces, with their tight junctions, constitute the first line of defense that ...
Scientific Contact: Yaffa Mizrachi
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A pharmacological Trojan horse approach to eradicate multidrug-resistant cancer (Technion)
The present technology describes an efficient method to eradicate multidrug resistance (MDR) tumor cells via lysosomal photodestruction ...
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A Process for Creating a Three – Dimensional Configuration on a Substrate (BGN)
Scientific Contact: Robert Marks
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A Specific Glycan Biomarker and Potential Drug Target for Amyotrophic Lateral Sclerosis (ALS) (BGN)
Amyotrophic Lateral Sclerosis (ALS) also named Lou Gehrig's disease, is a fatal neurodegenerative disease characterized by the progressive degeneration of cortical brain neurons, brainstem and, upper and lower motor neurons. Within short time, the disease leads to limb paralysis, compromise of ...
Scientific Contact: Rachel Glicklis-Lichtenstein
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Acyl-Coa: Diacylglycerol Acyltransferase 1-like Gene (PTDGAT1) and Uses Thereof (BGN)
Scientific Contact: Sammy Boussiba
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Adult stem cell-derived connective tissue progenitors for tissue engineering (Technion)
The present invention provides methods for generating and utilization of connective tissue progenitor cells from adult stem cells, successfully overcoming shortcomings of presently known configurations. Adult stem cells differentiate into connective tissue progenitor cells capable of being ...
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Alginate Biomaterials for Treating Liver Dysfunction and Disease (BGN)
Acute liver failure and chronic liver disease, such as hepatitis and cirrhosis, present a huge unmet medical need, with annual 1-2 million deaths worldwide. The liver is responsible for detoxification-removing and excreting body wastes and hormones, drugs and foreign substances, synthesis of plasma ...
Scientific Contact: Smadar Cohen
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