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16 technologies found
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The TechnologyTextiles that have been modified by integrating peptide nanostructures show remarkable properties. These include the physical and chemical properties of the fabric, such as strength and fire-resistance, as well as much more advanced properties including enzymatic activities such ...
Scientific Contact: Ehud Gazit
Turning Excellent Multidisciplinary Science into Therapeutic Leads HTS Biological assays unit:The research capabilities of the High Throughput Screening (HTS) and Biological Assays Unit at the BCDD include:Cell culture of multiple cell types modeling disease.Performance of a diverse range of ...
Scientific Contact: Ehud Gazit
The Technology Novel, self-assembled organic aromatic nano-peptides and nano-spheres which exhibit excellent properties such as stability, solubility, transparency and rigidness alongside basic peptide features. Nanotechnology benefits are achieved with biocompatible ingredients having a ...
Scientific Contact: Ehud Gazit
EG-30: clinical phase drug for AMD and Glaucoma EG-30 – the highlights: · Excellent safety profile in healthy volunteers and glaucoma patients • Low systemic exposure • No increase in IOP in glaucoma patients treated with EG-30 for 16days (eye ...
Scientific Contact: Ehud Gazit
The Technology A Peptide NanoForest, is a dense array of self assembling organic nanotubes, capable of enhancing sensitivity and selectivity parameters of amperometric electrode high-performance sensors. The patented Diphenylalanine (FF) aromatic dipeptide nanotubes are formed under mild ...
Scientific Contact: Ehud Gazit
The Technology An artificial ferredoxin-hydrogenase fusion enzyme (Fd-HydA) has been developed for the production of hydrogen gas in algae. The Fd-HydA fusion enzyme interferes with the formation of the naturally occurring ferredoxin-sugar production pathway in photosystem I (PSI) complex and ...
Scientific Contact: Iftach Yacoby
TechnologyStabilized human IAPP (hIAPP) oligomers were used for the development of active immunization of type 2 diabetes. This promising novel approach for the treatment of type 2 diabetes is doable due to the establishment of a new protocol for the formation of stable islet amyloid ...
Scientific Contact: Ehud Gazit
TechnologyThe aggregation site on human calcitonin has been identified, paving the way for development of specific inhibitors of calcitonin amyloid fibril formation. Such inhibitors will enable development of improved calcitonin therapeutics as well as greatly facilitate in vitro calcitonin ...
Scientific Contact: Ehud Gazit
The TechnologyProprietary peptide nanostructures1 can be readily fabricated on various surfaces including electrodes2,4. A physical vapor deposition method (PVD) allows the precise control on the molecular dimensions of the structures using industry standard techniques. These nanostructures ...
Scientific Contact: Ehud Gazit
Technology Reinforcement of common and proprietary polymers (plastics) and composite materials for coatings and casts with nano-additives in small percentages leads to improvement of anti crack, anti-scratch, anti-rust and anti-moisture properties. Novel, patented, self-assembled organic ...
Scientific Contact: Ehud Gazit
The TechnologyA spectroscopic, optical method for early detection of amyloid fibril formation in cerebrospinal fluid, as a non-destructive diagnostic tool for early detection of amyloid diseases.The core recognition motif of Aβ peptide is the di-phenylalanine (FF) element, which has been ...
Scientific Contact: Ehud Gazit
TechnologyWe developed nanostructures based on Peptide-Nucleic Acid (PNA) derivatives which show highly promising performance characteristics. The unique electroluminescence/photoluminescence materials can be used as emissive materials in manufacturing Organic Light-Emitting Diodes (OLED) with ...
Scientific Contact: Ehud Gazit
The TechnologyDisease modifying drugs for Alzheimer's disease (AD) and the related Mild Cognitive Impairment (MCI), based on rationally-designed quinone-based small molecules. Results so far resulted in significant reversal of AD symptoms while causing no apparent adverse effects. The ...
Scientific Contact: Ehud Gazit
The Technology A breakthrough Self Assembled Peptide Hydrogel (SAPH) has been developed. SAPH is a safe, self-assembled, biocompatible, remarkably strong hydrogel with modulated stability that is suitable for various medicinal and cosmetic applications. SAPH is based on the highly efficient ...
Scientific Contact: Ehud Gazit
TechnologyOrganic, aromatic di-peptide self-assemble into close-caged structures of tubes, spheres and hydrogels. These exhibit excellent properties such as stability, solubility, transparency and rigidness alongside the basic peptide features utilized in cosmetics. The materials can be ...
Scientific Contact: Ehud Gazit
Neuroretinal degeneration including age related macular degeneration (AMD) and Retinitis pigmentosa (RP) are the leading cause of vision incapacitation and blindness worldwide. Over 30 million people are affected, mostly elderly. Retinal degeneration can result from genetic defects affecting ...
Scientific Contact: Ehud Gazit
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*TTO - Technology Transfer Organization
ITTN - Israel Tech Transfer Organization