Technology Opportunities

There is currently no effective therapy for HD nor for most other neurodegenerative diseases. Some current approaches try to interfere with the aggregation of huntingtin (Htt), the misfolded protein that causes this disease. This may not be beneficial, as misfolded protein sequestration into ...

Lab DescriptionMain areas of interest are in the mechanisms of protein folding and trafficking in the early secretory pathway of mammalian cells and the development of ER stress upon their malfunction, particularly in neurodegenerative diseases. Specific research topics are:• Protein ...