Description: Monoclonal antibody to Galectin-8 (clone 106.1).
Galectin-8 is a secreted, integrin-binding protein, part of a mammalian lectins family. Galectin-8, also known as Prostate Cancer Tumor Antigen-1 (PCTA-1) is highly expressed in human prostate cancer. It was shown to trigger the transcription of a unique set of genes, some of which are associated with bone remodeling and prostate cancer progression.
Reference: Levy Y, Arbel-Goren R, Hadari YR, Eshhar S, Ronen D, Elhanany E, Geiger B, Zick Y. 2001. Galectin-8 functions as a matricellular modulator of cell adhesion. J Biol Chem. 276(33):31285-95.