Categories |
Interfacial phenomena, surfactant chemistry, emulsions, microemulsions, nanosized self-assembled liquids (NSSL), transdermal/transmembrane transport, nutraceuticals, hydrocolloids, drug delivery systems, lyotropic liquid crystals (LLC) |
Objective/function
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The laboratory is active in the fields of synthetic organic chemistry of surfactants; physical chemistry; surface and colloid science - emulsion technology, crystallization phenomena, extraction processes; nutraceuticals; drug delivery vehicles - nanosized self-assembled liquid (NSSL) vehicles; lyotropic liquid crystals (LLC) – related to cubosomes and hexosomes; novel liquid micellar discontinuous phases - the QL phase; bioavailability of nutraceuticals and drugs; and competitive adsorption (cholesterol and phytosterols)
Research provided
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Research on new or modified nanosized self-assembled liquids (NSSL)
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Construction of specific and regioselective organic (signature flavoring and aroma molecules) and enzymatic (phospholipids, monoglycerides) products
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Developing new polymorphic crystals (drugs, sweeteners, nutraceuticals) using nanodroplets as nanoreactors
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Solubilization of insoluble active molecules (drugs and nutraceuticals) and using nanovehicles to transport the guest molecules to food products and via the digestive tracts to the blood stream
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Competitive solubilization of bioactives at interfaces of microemulsions
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Stabilization (physically or chemically) of sensitive molecules against oxidation
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Controlled release of active molecules from the core of the dispersed system (microemulsion, microcapsule) to the outer continuous interface
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Design new emulsifiers
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Modify proteins and hydrocolloids to form nanosized aggregates
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Improve solubilization via emulsified microemulsions (modified double emulsions) with controlled release
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Food emulsions and interfacial modifications
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Nutraceuticals - solubilization and characterization
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Novel double emulsions – emulsified microemulsions (EME)
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Transdermal and transmembrane drug delivery
Advantages
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Highly skilled, experienced staff employing state-of-the-art equipment/technologies
Contact
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Nissim Garti, PhD, garti@vms.huji.ac.il
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Link to homepage http://chem.ch.huji.ac.il/applsci/ac/garti/