Technology Opportunities

Objective/function

The Protein Purification Facility provides consultation, information and assistance to researchers and students as well as biotech and pharmaceutical companies interested in protein purification

Research provided

• Develop, optimize and upscale protocols for protein purification from samples of different sources; design purification strategy according to each protein
• Protein purification for structural studies like X-ray crystallography or NMR
• Tools for protein characterization and refolding
• Tools to increase solubility and/or stability of proteins as well as their ability to crystallize
• Courses in protein purification and expression
• Active support and consultation

Advantages

• The Protein Purification Facility is the only place in Israel that provides such comprehensive services, leveraging our unique equipment and wide experience

Client record

• We are actively involved in significant collaboration in structural and biochemical studies, isolation, and identification of new proteins. Past commercial clients include SimetraPharm, MGVS, AFFISINK, MaimoniDex RA, TEVA-ABIC

Available equipment

• Complete and fully automated liquid chromatography system designed for method development and research applications
• Columns and resins for purification according to size, charge, hydrophobicity and substrate affinity
• Gel electrophoresis and IEF (isoelectric focusing) apparatus
• Cell disruption, blotting and ultrafiltration systems

Staff

• Mario Lebendiker, PhD, Head of the Facility

Contact

Mario Lebendiker, PhD, mariol@mail.ls.huji.ac.il, tel.: 972-2-658-6920

Link to homepage http://wolfson.huji.ac.il/purification/index.html