Combinatorial libraries of heterocyclic compounds
Category |
Drug Discovery, Small Molecules, Conversion of Peptides and Proteins into drug leads |
Development Stage |
Ongoing projects in various stages |
Patent Status |
Patents published in U.S. and Europe, filed in Israel |
Market Size |
The global protein therapeutic market was valued in excess of US$ 57 billion in 2006, growing at a CAGR of 12.83% till 2010 |
Highlights
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Preparing libraries of backbone cyclized peptidomietics and macromoecules with conformational diversity, based on active residues from proteins and/or active peptides for screening and selecting drug lead candidates, having improved activity, selectivity, metabolic stability and enhanced intestinal permeability. This technology is applicable to a variety of indications in human medicine, veterinary medicine and in agriculture
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Applying this novel technology to a patented target molecule facilitates the speedy development of drug leads
Our Innovation
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A new technology that converts active regions in proteins and peptides into orally available drug leads.
Key Features
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Faster, more reliable, identification of drug leads
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Enables faster pharmacological studies
Development Milestones
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Cooperation with companies with defined clinical goals and patented molecules to develop drug leads
The Opportunity
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Licensing agreements with cooperation partners to convert their peptides and proteins into drug leads using new technology
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Libraries of drug candidates sold to partners