Categories |
Diagnostics, Fertility, Saliva |
Development Stage |
Ovulation: validation in females saliva, Pregnancy: kit optimization in reconstituted females saliva samples |
Patent Status |
National Phase |
Market |
Women health – 8 billion US Dollars |
Highlights
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We are developing saliva-based fertility diagnostic kits for early detection of pregnancy as well as a kit for ovulation prediction, to serve as user-friendly alternatives for commercial urine/serum-based tests.
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Saliva is an ideal bio-fluid: sample collection is easy, inexpensive and non-invasive and it allows fast detection accompanied by a comfortable process and reduced user anxiety, hence it's suitable for home use.
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The group specializes in salivary research including salivary biomarkers discovery and saliva based lateral flow immunoassays (LFIS) development.
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Since saliva possesses inhibition characteristics that reduce the detectability of point of care (POC) technology, we developed a unique, proprietary technology that amplifies fertility hormones visualization and allows their detection in saliva in a self-manufactured LFIS We aim at developing the first saliva based ovulation and pregnancy test kits.
Our Innovation
Adapted LFIS which allows enhanced sensitivity detection of hCG and LH in saliva.
Development Milestones
Ovulation
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Pre-Clinical trials: daily monitoring and calibration of LH level in saliva of 20 women cycles, observed in self-manufactured LFIS and comparison to urine.
Pregnancy
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Pre-Clinical trials: hCG detection in 20 saliva samples taken from early stage of pregnancy (7 days menstrual cycle delay).
The Opportunity
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The women fertility market is estimated to be over 8 billion US Dollars.
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Current technology offers only blood/urine based diagnostic – there are no saliva based commercial kits.
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Current urine based Ovulation kits are not reliable and accurate enough
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Saliva based fertility test suggests more attractive, friendly, esthetical and comfortable detection processes than the currently urine based test.
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The market size and the convenience which saliva-based test offer, prophesying its ability to takeover considerable segments of this huge market, hence being highly profitable.