Technology Opportunities

BGN (42)
BioRap (8)
BIRAD (5)
Mor (5)
Ramot (70)
Technion (25)
Tel Hashomer (13)
Yissum (38)
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Casein particles encapsulating therapeutically active agents. (Technion)
The present technology describes a novel oral drug delivery system for drug resistance gastric cancers. Comprising a hydrophobic chemotherapeutic drug and a chemosensitizer entrapped within nanoparticles of beta casein (β-CN), which self-associates into micelles. ...
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Cell manipulation using nanoparticles and short laser pulses (Technion)
The present technology involves the use of nanoparticles and laser light to manipulate selected cells for cancer therapy, tissue regeneration and drug ...
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Cell Therapy for Diabetes: Expansion and re-differentiation of adult human pancreatic islet cells for transplantation (Ramot)
The insulin-producing pancreatic islet β cells are destroyed in type 1 diabetes (T1D) by autoimmunity, and malfunction in type 2 diabetes (T2D), which together afflict >5% of world population. Restoration of a functional β-cell mass by regeneration or transplantation represents the ...
Scientific Contact: Shimon Efrat
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Cell Therapy to Neurodegenerative Diseases (BGN)
Scientific Contact: Alon Monsonego
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Cells containing a nanopatch sensor in their membrane (BGN)
Scientific Contact: Jelinek Raz
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Cellular Functional Testing and Acquisition (Ramot)
Industrial Research Services: 1. Bone cells in culture – We offer a bone marrow derived bone-like tissue in culture for testing the effect of various factors, hormones, drugs etc. on bone cells proliferation, differentiation and mineralization. The model is described in the following ...
Scientific Contact: Naphtali Savion
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Ceramide-based Liposomal Drug for the Treatment of Multi-Drug Resistant Cancer (Yissum)
Category Life Sciences and Bio Technology Keywords Chemotherapy, Drug resistance * The project is conducted in collaboration with Memorial Sloan-Kettering Cancer Center. Application Cells with multidrug resistance (MDR) due to aberrant expression of the lipid transporter ...
Scientific Contact: Yechezkel Barenholz
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Chemical Preparation of Polyubiquitin Chains (BGN)
Scientific Contact: Ashraf Brik
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Chemical Preparation of Ubiqitin Thioesters and Modifications Thereof (BGN)
Scientific Contact: Ashraf Brik
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Combinations of corroles and statins (Technion)
High blood cholesterol level is a main and well established risk factor for the development of cardiovascular disease. Statins, inhibitors of cholesterol biosynthesis, are the leading drugs for reducing cholesterol levels and the most prescribed pharmaceuticals worldwide. We have created ...
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Composition Comprising Red Microalgae Polysaccharides and Metals (BGN)
Scientific Contact: Shoshana Arad (Malis)
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Compositions and Methods for Diagnosing and Treating an Inflammation (Technion)
A method of treating multiple sclerosis (MS) in a subject in need thereof, the method comprising administering to said subject a therapeutically effective amount of an isolated polypeptide comprising an antigen recognition ...
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Compositions for treating ophthalmic medical conditions (Ramot)
Additional information can be provided upon ...
Scientific Contact: Michael Belkin
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Conjugates of a Phospholipid and a Drug for the Treatment of Inflammatory Bowel Disease (BGN)
Scientific Contact: Arik Dahan
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Corroles for treatment of diseases (Technion)
Corroles are synthetic, porphyrin molecules that can act as catalytic antioxidants. Corrole derivatives can be used for lowering the probability of developing chronic kidney disease, especially diabetic nephropathy, for which there are currently no approved therapeutic drugs. Additionally, they ...
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Deep nanopatterning focused ion beam technology (Technion)
Focused ion beam (FIB) technology is widely used in the semiconductor industry. FIB etching is used to develop and modify optoelectronic and microelectronic devices. However, FIB technology is limited to large scale devices and is incompatible with the industry trend to reduce device dimensions. ...
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Desaturase Defective Mutant Gene Use Thereof (BGN)
Scientific Contact: Sammy Boussiba
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Development of Anti Necrotic Drugs for Prevention (BGN)
Cell death can occur through two main mechanisms, apoptosis or necrosis. Apoptosis is a tightly regulated physiological process and many of the biochemical pathways involved are well characterized. Necrosis, the outcome of severe and acute injury, has been until lately generally viewed as an ...
Scientific Contact: Eli Lewis
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Drug Screening Animal Model for Anti-compulsive Activity (Ramot)
We have developed the signal attenuation rat model of obsessive-compulsive disorder (OCD). This model is based on the theoretical proposition that compulsive behaviors result from a deficit in the feedback, which is associated with the performance of normal goal-directed responses. In our ...
Scientific Contact: Daphna Joel
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Drug Treatments Targeting Glioma Microenvironment: CD38 inhibitor as a Potential Therapeutic Approach for Glioma Treatment (Ramot)
OUTLINE CD38 is an ectoenzyme that generates Ca2+ mobilizing agents and regulates nicotinamide adenine dinucleotide (NAD) levels. We showed that via its enzymatic activity CD38 promotes the supporting role of tumor microenvironment (TME) cells in brain and extracranial cancers.1-3 In addition, ...
Scientific Contact: Reuven Stein
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