Technology Opportunities

BGN (42)
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Yeda (41)
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Chemical Preparation of Ubiqitin Thioesters and Modifications Thereof (BGN)
Scientific Contact: Ashraf Brik
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Cholesterol Antibodies (Yeda)
Summary Description: Monoclonal antibodies specific for cholesterol/ceramide-rich domains (clones 405F, 14F, 499F) and cholesterol micro-domains (clones 36A1, 5881) in cell membranes.Originally raised against an artificial monolayer of lipid mixtures in, and were shown to specifically label the ...
Scientific Contact: Lia Addadi
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Combinations of corroles and statins (Technion)
High blood cholesterol level is a main and well established risk factor for the development of cardiovascular disease. Statins, inhibitors of cholesterol biosynthesis, are the leading drugs for reducing cholesterol levels and the most prescribed pharmaceuticals worldwide. We have created ...
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Composition Comprising Red Microalgae Polysaccharides and Metals (BGN)
Scientific Contact: Shoshana Arad (Malis)
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Compositions and Methods for Diagnosing and Treating an Inflammation (Technion)
A method of treating multiple sclerosis (MS) in a subject in need thereof, the method comprising administering to said subject a therapeutically effective amount of an isolated polypeptide comprising an antigen recognition ...
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Conjugates of a Phospholipid and a Drug for the Treatment of Inflammatory Bowel Disease (BGN)
Scientific Contact: Arik Dahan
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Corroles for treatment of diseases (Technion)
Corroles are synthetic, porphyrin molecules that can act as catalytic antioxidants. Corrole derivatives can be used for lowering the probability of developing chronic kidney disease, especially diabetic nephropathy, for which there are currently no approved therapeutic drugs. Additionally, they ...
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Deep nanopatterning focused ion beam technology (Technion)
Focused ion beam (FIB) technology is widely used in the semiconductor industry. FIB etching is used to develop and modify optoelectronic and microelectronic devices. However, FIB technology is limited to large scale devices and is incompatible with the industry trend to reduce device dimensions. ...
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Desaturase Defective Mutant Gene Use Thereof (BGN)
Scientific Contact: Sammy Boussiba
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Development of Anti Necrotic Drugs for Prevention (BGN)
Cell death can occur through two main mechanisms, apoptosis or necrosis. Apoptosis is a tightly regulated physiological process and many of the biochemical pathways involved are well characterized. Necrosis, the outcome of severe and acute injury, has been until lately generally viewed as an ...
Scientific Contact: Eli Lewis
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Disrupting or Preventing Formation of Biofilm by Enzyme Inhibitors (Yeda)
Summary Biofilm is a complex colony of bacteria, which are attached together by extracellular polymeric substance. This setting provides the bacteria protection against environmental factors, improves their surface attachment, and plays a major role in resistance to treatment. Therefore, biofilms ...
Scientific Contact: Ilana Kolodkin-Gal
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DOPAMINE NANOCAPSULES AND USES THEREOF (BIRAD)
The ProblemThe presence of microbial contamination of surfaces poses a serious problem from the point of view of health protection. There is a growing market demand to improve effectivity, safety, endurance and cost of anti-microbial coating.The SolutionWe propose a novel bio-inspired nanocapsule ...
Scientific Contact: Shai Rahimipour
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Effective Nanoscale Delivery System as an anti-Leishmania drug/ technological platform for drug delivery (BIRAD)
BACKGROUNDLeishmania parasites cycle between two hosts, insect host and mammalian macrophages. Infection in the mammalian host is caused by proliferation within macrophages, especially present in liver and spleen (visceral) or within macrophages in the skin (cutaneous Leishmaniasis). Leishmania ...
Scientific Contact: Shulamit Michaeli
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ERBB2 as a Novel Target to Treat Heart Failure by Inducing Cardiomyocyte Proliferation (Yeda)
Summary Existing treatments fail to compensate the irreversible loss of functional cardiomyocytes (CM), thus presenting a major medical unmet need. Inducing native CM replacement is one approach being tested as regenerative treatment, with the advantage of a more straightforward methodology over ...
Scientific Contact: Eldad Tzahor
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Extracellular matrix metalloproteinase inducer (EMMPRIN) peptides and binding antibodies (Technion)
Isolated peptides from the protein EMMPRIN (CD147/Basigin) and antibodies directed against antigenic determinants within the ...
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Foam for pulmonary drug delivery (Technion)
The invention, provides a method and a device for delivery of foam to a target site of a respiratory ...
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Fragments of NKp44 and Nkp46 for Targeting Viral Infected and Tumor Cells (BGN)
Scientific Contact: Angel Progador
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Fully Naive Induced Human Pluripotent Stem Cells (iPSC) (Yeda)
Summary A novel method to revert human iPSC to a fully naive state, retaining stable pluripotency. The feasibility for the existence of ground state naive pluripotency in human embryonic stem cells (hESC) has long been researched. This innovative technology supplies the composition of chemically ...
Scientific Contact: Jacob (Yaqub) Hanna
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Gamma-ray detector (Technion)
Gamma-ray detectors have wide applications in fields such as nuclear medicine, environmental monitoring and material testing. By analyzing emitted rays using a gamma-ray spectrometer, diagnostically useful information can be obtained. Some of the methods used for the detection of gamma-rays ...
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Heparanase-neutralizing monoclonal antibodies (Technion)
The present invention relates to heparanase-neutralizing monoclonal antibodies (m Abs), pharmaceutical composition comprising same, and use thereof for treating a disease or disorder associated ...
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