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207 technologies found
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Our Innovation Based on a provocative working hypothesis, we most probably identified the molecular origin of insulin resistance (IR). Systemic IR is induced via post-translational modification (PTM) of liver key regulatory proteins. We have discovered that hepatic futile utilization of ...
Scientific Contact: Shmuel Ben-Sasson
Scientific Contact: Claude Brodski
Background There is a growing demand in the field of biological drugs for improved protein expression platforms. Consequently there is a need for affordable manufacturing methods. Our Innovation A new concept of vector design that incorporates a gene-specific enhanced translation elements and ...
Scientific Contact: Boaz Tirosh
Controlled drug delivery systems offer numerous advantages compared to conventional dosage forms including improved efficacy, reduced toxicity, and improved patient compliance and convenience. Controlled release systems aim to improve the effectiveness of drug therapy. This improvement can take ...
Scientific Contact: Smadar Cohen
A subchondral defect is usually characterized by a structural breakdown of the articular cartilage and the bone underneath due to trauma or disease, leading to chronic disabilities. Treating such defects is an important medical target since in the adult patient, damaged cartilage cannot ...
Scientific Contact: Smadar Cohen
A Novel Non-Hormonal Composition as Contraceptive for Ovulation Ariel Hourvitz, Yuval Yung, Svetlana Markman and Gil Yerushalmi, Sheba Medical Center Categories Women Health , Contraceptive Composition, Fertility, Non Hormonal Development Stage Preclinical studies – efficacy and ...
A Novel Non-Hormonal Composition as Contraceptive for Ovulation Ariel Hourvitz, Yuval Yung, Svetlana Markman and Gil Yerushalmi, Sheba Medical Center Categories Women Health , Contraceptive Composition, Fertility, Non Hormonal Development Stage Preclinical studies – efficacy and ...
The present technology describes the caspase-3/YAP module as a new target for the treatment of melanoma development and ...
Background A nonsense mutation is an alteration in the genetic code that prematurely halts the synthesis of an essential protein, such as dystrophin in Duchenne muscular dystrophy. Nonsense mutations caused by premature stop codon, are treated using read-through therapies that are only ...
Scientific Contact: Rotem Karni
Background Glaucoma is a disease characterized by intra-ocular pressure sufficient to damage the optic nerve and cause permanent impairment of vision. Glaucoma is rarely cured, but its progression can be greatly delayed by reducing the intra-ocular pressure with medicines, laser procedure or ...
Scientific Contact: Orna Geyer
The present technology describes an efficient method to eradicate multidrug resistance (MDR) tumor cells via lysosomal photodestruction ...
Background Methylene lactone structures are frequently observed as scaffold segments of various biochemical compounds. These architectures have been identified as building blocks of numerous terpenoids, as well as other families of diverse and often remotely related metabolites. A ...
Scientific Contact: Dmitry Tsvelikhovsky
The Biomaterials and Corrosion LaboratoryIby and Aladar Fleischman Faculty of Engineering, Tel-Aviv University, Israel In line with the demands of modern society, the multidisciplinary Biomaterials and Corrosion Laboratory is conducting strategic R&D on advanced materials ranging from ...
Scientific Contact: Noam Eliaz
Acute liver failure and chronic liver disease, such as hepatitis and cirrhosis, present a huge unmet medical need, with annual 1-2 million deaths worldwide. The liver is responsible for detoxification-removing and excreting body wastes and hormones, drugs and foreign substances, synthesis of plasma ...
Scientific Contact: Smadar Cohen
Inflammation often named “the secret killer” is a key factor in a large group of diseases affecting and killing millions of people every year. Examples of inflammatory diseases or diseases with key inflammatory components include Arthritis, Alzheimer, Parkinson, ALS, Peritonitis, Colitis, ...
Scientific Contact: Rachel Levy
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